1. Lithium contamination of honeybee products and its accumulation in brood as a consequence of anti-varroa treatmentJanez Prešern, Uroš Kur, Jernej Bubnič, Martin Šala, 2020 Ključne besede: honeybees, lithium, lithium contamination, varroa, varroa control, food chain coupling
Objavljeno: 16.06.2020; Ogledov: 2180; Prenosov: 1073
 Datoteka (515,51 KB)
Prenosov v tednu: 582 |
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3. Identification of three anatomical patterns of the spinal accessory nerve in the neck by neurophysiological mappingBoštjan Lanišnik, Miha Žargi, Zoran Rodi, 2014 Opis: Background. In spite of preservation of the accessory nerve there is still considerable proportion of patients with partial nerve damage during modified radical neck dissection (MRND). Methods. The nerve was identified during the surgery and its branches for the trapezius muscle mapped with nerve monitor. Results. The accessory nerve was mapped during 74 hemineck dissections and three patterns were identified. In type 1 nerve exits at the posterior end of the sternocleidomastoid muscle (SCm) and then it enters the level V (66 %). In type 2 the nerve for trapezius muscle branches off before entering the SCm (22 %). In type 3 the nerve exits at the posterior part of the SCm and it joins to the cervical plexus (12 %). The nerve than exits this junction more medially as a single trapezius branch. Conclusions. The description of three anatomical patterns in level II and V could help preserving the trapezius branch during MRND.
Ključne besede: spinal accessory nerve, nerve mapping, neck dissection, anatomy, shoulder disability
Objavljeno: 11.04.2024; Ogledov: 189; Prenosov: 38
Celotno besedilo (1,66 MB)
Prenosov v tednu: 21 |
4. Minimally invasive CT guided treatment of intraspinal synovial cystSergeja Kozar, Miran Jeromel, 2014 Opis: Background. Intraspinal synovial cysts of vertebral facet joints are uncommon cause of radicular pain as well as neurological deficits. They can be managed both conservatively and surgically.Case report. A 77-year old polymorbid patient presented with bilateral low back pain which worsened during the course of time and did not respond to the conservative treatment. A diagnosis of intraspinal synovial cyst was made using the magnetic resonance imaging (MRI). Percutaneous computed tomography (CT) guided injection with installation of local anesthetic together with corticosteroid and rupture of the cyst was successfully used. A month after the procedure his pain improved, the usage of analgesics diminished and his over-all quality of life improved.Conclusions. Percutaneous CT guided lumbar synovial cyst treatment is safe and reliable alternative to the surgical treatment in polymorbid patients with radiculopathy who are not able to tolerate general anesthesia and operation.
Ključne besede: ciste, intraspinalne sinovialne ciste, bolečina, zdravljenje, radiologija
Objavljeno: 11.04.2024; Ogledov: 66; Prenosov: 34
Celotno besedilo (515,68 KB)
Prenosov v tednu: 21 |
5. Glioblastoma patients in Slovenia from 1997 to 2008Uroš Smrdel, Viljem Kovač, Mara Popović, Matjaž Zwitter, 2014 Opis: Glioblastoma is the most common primary brain tumour. It has a poor prognosis despite some advances in treatment that have been achieved over the last ten years. In Slovenia, 50 to 60 glioblastoma patients are diagnosed each year. In order to establish whether the current treatment options have any influence on the survival of the Slovenian glioblastoma patients, their data in the period from the beginning of the year 1997 to the end of the year 2008 have been analysed. Patients and methods. All patients treated at the Institute of Oncology Ljubljana from 1997 to 2008 were included in the retrospective study. Demographics, treatment details, and survival time after the diagnosis were collected and statistically analysed for the group as a whole and for subgroups. Results. From 1997 to 2008, 527 adult patients were diagnosed with glioblastoma and referred to the Institute of Oncology for further treatment. Their median age was 59 years (from 20 to 85) and all but one had the diagnosis confirmed by a pathologist. Gross total resection was reported by surgeons in 261 (49.5%) patients; good functional status (WHO 0 or 1) after surgery was observed in 336 (63.7%) patients, radiotherapy was performed in 422 (80.1%) patients, in 317 (75.1%) of them with radical intent, and 198 (62.5 %) of those received some form of systemic treatment (usually temozolomide). The median survival of all patients amounted to 9.7 months. There was no difference in median survival of all patients or of all treated patients before or after the chemo-radiotherapy era. However, the overall survival of patients treated with radical intent was significantly better (11.4 months; p < 0.05). A better survival was also noticed in radically treated patients who received additional temozolomide therapy (11.4 vs. 13.1 months; p = 0.014). The longer survival was associated with a younger age and a good performance status as well as with a more extensive tumour resection. In patients treated with radical intent, having a good performance status, and receiving radiotherapy and additional temozolomide therapy, the survival was significantly longer, based on multivariate analysis.
Ključne besede: glioblastoma, treatment, survival, surgery, radiotherapy, termozolomide
Objavljeno: 11.04.2024; Ogledov: 70; Prenosov: 33
Celotno besedilo (423,05 KB)
Prenosov v tednu: 20 |
6. Injective coloring of graphs revisitedBoštjan Brešar, Babak Samadi, Ismael G. Yero, 2023 Opis: An open packing in a graph $G$ is a set $S$ of vertices in $G$ such that no two vertices in $S$ have a common neighbor in $G$. The injective chromatic number $\chi_i(G)$ of $G$ is the smallest number of colors assigned to vertices of ▫$G$▫ such that each color class is an open packing. Alternatively, the injective chromatic number of $G$ is the chromatic number of the two-step graph of $G$, which is the graph with the same vertex set as $G$ in which two vertices are adjacent if they have a common neighbor. The concept of injective coloring has been studied by many authors, while in the present paper we approach it from two novel perspectives, related to open packings and the two-step graph operation. We prove several general bounds on the injective chromatic number expressed in terms of the open packing number. In particular, we prove that $\chi_i(G) \ge \frac{1}{2}\sqrt{\frac{1}{4}+\frac{2m-n}{\rho^{o}}}$ holds for any connected graph $G$ of order $n\ge 2$, size $m$, and the open packing number ${\rho^{o}}$, and characterize the class of graphs attaining the bound. Regarding the well known bound $\chi_i(G)\ge \Delta(G)$, we describe the family of extremal graphs and prove that deciding when the equality holds (even for regular graphs) is NP-complete, solving an open problem from an earlier paper. Next, we consider the chromatic number of the two-step graph of a graph, and compare it with the clique number and the maximum degree of the graph. We present two large families of graphs in which $\chi_i(G)$ equals the cardinality of a largest clique of the two-step graph of $G$. Finally, we consider classes of graphs that admit an injective coloring in which all color classes are maximal open packings. We give characterizations of three subclasses of these graphs among graphs with diameter 2, and find a partial characterization of hypercubes with this property.
Ključne besede: two-step graph of a graph, injective coloring, open packing, hypercubes
Objavljeno: 09.04.2024; Ogledov: 57; Prenosov: 37
Celotno besedilo (460,72 KB)
Prenosov v tednu: 20 |
7. Distant metastasis of rectal adenocarcinoma in a temporary tracheostomaRobert Šifrer, Primož Strojan, Nina Zidar, Miha Žargi, Aleš Grošelj, Milena Krajinović, 2014 Ključne besede: temporary tracheostoma, distant metastasis, rectal adenocarcinoma, rak (medicina), traheostoma, zasevki, metastaziranje, žlezni rak
Objavljeno: 11.04.2024; Ogledov: 62; Prenosov: 35
Celotno besedilo (1,21 MB)
Prenosov v tednu: 19 |
8. Mediastinal teratoma with hydrops fetalis in a newborn and development of chronic respiratory insufficiencyMilanka Simončič, Silvester Kopriva, Živa Zupančič, Maja Jerše, Janez Babnik, Matevž Srpčič, Štefan Grosek, 2014 Opis: Background. Mediastinal fetal teratoma can be detected as a mass in the chest during a routine prenatal ultrasound screening. Because of the pressure on mediastinal structures it can be the cause of non-immune hydrops fetalis and polyhydramnion. The development of hydrops fetalis leads to fetal death or premature delivery in most reported cases. Early surgical removal is important, but, the result of treatment depends on the stage of development of mediastinal organs and complications in the postoperative period. Case report. A 31-year-old gravida carrying twins, with spontaneous membrane rupture at 32 weeks gestation underwent urgent caesarean section after antenatal ultrasound revealed severe polyhydramnion and hydrops fetalis in geminus A. The child was intubated immediately after birth due to severe respiratory distress. Ultrasound and X-ray revealed a tumour mass in the right hemithorax. Tumour resection was performed at the age of 7 days. Histology examination revealed an encapsulated immature teratoma. The postoperative course was complicated with respiratory insufficiency which turned into chronic at the age of eight months. Conclusion. This is the fifth reported child with fetal mediastinal teratoma and severe hydrops fetalis that survived the neonatal period. Additional diagnostic search revealed abnormal course of both pulmonary arteries, which was probably one of the main causes of respiratory insufficiency.
Ključne besede: mediastinal teratoma, non-immune hydrops fetalis, diaphragm paralysis, chronic respiratory insufficiency, novorojenčki, mediastinalni teratom, kronična respiratorna insuficienca
Objavljeno: 11.04.2024; Ogledov: 75; Prenosov: 34
Celotno besedilo (1,29 MB)
Prenosov v tednu: 19 |
9. Cardiotoxicity of concomitant radiotherapy and trastuzumab for early breast cancerTanja Marinko, Jure Dolenc, Cvetka Bilban-Jakopin, 2014 Opis: Background. Trastuzumab therapy given in combination with one of several chemotherapy regimens is currently considered the standard of care for the treatment of early-stage, human epidermal growth factor receptor-2 (HER2) -positive breast cancer. The treatment with trastuzumab is due to a significant impact on the survival part of the standard adjuvant treatment of patients with HER2-positive breast cancer. Patients treated with postoperative breast or chest wall irradiation receive trastuzumab concomitant with radiotherapy. In a small proportion of patients trastuzumab causes cardiotoxicity. Preclinical findings indicate a radiosensibilizing effect of trastuzumab in breast cancer cells, but it is not yet clear whether it radiosensibilizes cells of healthy tissues too.Conclusions. Special attention is required when left breast or left thoracic wall is irradiated in patient receiving trastuzumab, because long-term effects of the concurrent treatment with trastuzumab and radiotherapy are not yet known. In an era where more patients are surviving a diagnosis of breast cancer, better understanding and earlier detection of therapy-induced cardiac toxicity will be of paramount importance.
Ključne besede: radiotherapy, cardiotoxicity, trastuzumab, early breast cancer
Objavljeno: 11.04.2024; Ogledov: 53; Prenosov: 31
Celotno besedilo (817,95 KB)
Prenosov v tednu: 18 |
10. Maker-Breaker domination game on trees when Staller winsCsilla Bujtás, Pakanun Dokyeesun, Sandi Klavžar, 2023 Opis: In the Maker-Breaker domination game played on a graph $G$, Dominator's goal is to select a dominating set and Staller's goal is to claim a closed neighborhood of some vertex. We study the cases when Staller can win the game. If Dominator (resp., Staller) starts the game, then $\gamma_{\rm SMB}(G)$ (resp., $\gamma_{\rm SMB}'(G)$) denotes the minimum number of moves Staller needs to win. For every positive integer $k$, trees $T$ with $\gamma_{\rm SMB}'(T)=k$ are characterized and a general upper bound on $\gamma_{\rm SMB}'$ is proved. Let $S = S(n_1,\dots, n_\ell)$ be the subdivided star obtained from the star with $\ell$ edges by subdividing its edges $n_1-1, \ldots, n_\ell-1$ times, respectively. Then $\gamma_{\rm SMB}'(S)$ is determined in all the cases except when $\ell\ge 4$ and each $n_i$ is even. The simplest formula is obtained when there are at least two odd $n_i$s. If ▫$n_1$▫ and $n_2$ are the two smallest such numbers, then $\gamma_{\rm SMB}'(S(n_1,\dots, n_\ell))=\lceil \log_2(n_1+n_2+1)\rceil$▫. For caterpillars, exact formulas for $\gamma_{\rm SMB}$ and for $\gamma_{\rm SMB}'$ are established.
Ključne besede: domination game, Maker-Breaker game, Maker-Breaker domination game, hypergraphs, trees, subdivided stars, caterpillars
Objavljeno: 08.04.2024; Ogledov: 71; Prenosov: 36
Celotno besedilo (255,58 KB)
Prenosov v tednu: 18 |