1. Lithium contamination of honeybee products and its accumulation in brood as a consequence of anti-varroa treatmentJanez Prešern, Uroš Kur, Jernej Bubnič, Martin Šala, 2020 Ključne besede: honeybees, lithium, lithium contamination, varroa, varroa control, food chain coupling
Objavljeno: 16.06.2020; Ogledov: 2180; Prenosov: 1073
 Datoteka (515,51 KB)
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2. Decrease in cellular nanovesicles concentration in blood of athletes more than 15 hours after marathonZala Jan, Mitja Drab, Damjana Drobne, Apolonija Bedina Zavec, Mojca Benčina, Barbara Drašler, Matej Hočevar, Judita Lea Krek, Ljubiša Pađen, Manca Pajnič, Neža Repar, Boštjan Šimunič, Roman Štukelj, Veronika Kralj-Iglič, 2021 Opis: Introduction: Cellular nanovesicles (CNVs), that are shed from cells, have been recognized as promising indicators of health status. We analyzed the effect of long-distance running on concentration of CNVs, along with some standard blood parameters, in 27 athletes two days before and > 15 hours after physical effort. Methods: CNVs were isolated by repetitive centrifugation and washing of samples, and assessed by flow cytometry. Cholinesterase (ChE) and glutathione S-transferase (GST) activity were measured spectrophotometrically. Interleukin 6 (IL-6) and tumor necrosis factor-% (TNF-%) concentrations were measured using enzyme-linked immunosorbent assay (ELISA). C-reactive protein (CRP) was measured with immunoturbidimetric determination and lipidogram parameters were measured by enzymatic colorimetric assay. Flow cytometry was used for blood cell count and mean platelet volume (MPV) measurement. Results: More than 15 hours after physical effort a decrease was found in CNVs% concentration in isolates from blood (46%; p< 0.05), in ChE activity in whole blood (47%; p< 0.001), in plasma (34%; p< 0.01), and in erythrocyte suspension (54%; p< 0.001), as well as in GST activity in erythrocyte suspension (16%; p< 0.01) and in IL-6 concentration in plasma (63%; p< 0.05). We found no change in GST activity in plasma and in TNF-% concentration in plasma. Correlations (> 0.8; p< 0.001) between CNVs% concentration and ChE activity, and GST activity, respectively, in erythrocyte suspension were found. Conclusion: We found that > 15 hours post-physical effort, CNVs% concentration was below the initial value, concomitant with other measured parameters: ChE and GST activity as well as IL-6 concentration, indicating a favorable effect of physical effort on health status. CNVs% concentration and ChE activity in isolates from peripheral blood proved to have potential as indicators of the response of the human body to inflammation after physical effort. Physical activity should be considered as an important factor in preparation of subjects for blood sampling in procedures focusing on CNV-containing diagnostic and therapeutic compounds.
Ključne besede: membrane vesiculation, physical effort, blood samples, inflammation process, cellular nanovesicles, marathon
Objavljeno: 25.01.2021; Ogledov: 1274; Prenosov: 1585
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6. Zapoved in zločin : stičišča prava, književnosti in teorijeMatej Accetto, Matjaž Ambrož, Matjaž Jager, Andrej Kristan, Mitja Muršič, Jurij Novak, Goran Č. Potočnik, Jernej Pribošič, John Stubbs, Aleš Završnik, 2012 Ključne besede: kriminologija, pravo, književnost
Objavljeno: 27.11.2015; Ogledov: 5959; Prenosov: 1287
Celotno besedilo (205,01 MB)
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7. Investigations of chemical element distributions in soil, North Macedonia—a reviewTrajče Stafilov, Robert Šajn, Jasminka Alijagić, 2024 Opis: This review article considers the following aspects: naturally distributed chemical elements and their enrichments, and the increased occurrence of PTEs due to anthropogenic and urban activities, as well as due to the geochemical uniqueness of certain geochemical landscapes, depending on the lithological environment. The review article is the result of many years of successful cooperation between the Geological Survey of Slovenia and the Faculty of Natural Sciences in Skopje, Ss. Cyril and Methodius University in Skopje, as well as several other institutions from North Macedonia, Russia and Romania but, also, through the voluntary and enthusiastic work of Prof. Trajče Stafilov’s PhD and Master’s students. To create the Geochemical Atlas, the territory of North Macedonia was covered with 995 sampling locations, but 16 separate areas with soil contamination were additionally sampled. The total sum of all collected soil samples was 3983 from 2449 different sampling sites in the period from 2006 to 2017. The analyses were performed at the Institute of Chemistry, Faculty of Natural Sciences in Skopje, at the Ss. Cyril and Methodius University in Skopje, North Macedonia, at the Research Institute for Analytical Instrumentation (ICIA), Cluj-Napoca, Romania, at the Joint Institute for Nuclear Research in Dubna, Moscow Region, Russia, and at Acme Labs in Vancouver, Canada. The sum of all analysed soil samples in all four mentioned laboratories was 7991 from 2006 to 2017. Using advanced mathematical methods such as multivariate statistical methods (HCA, FA, PCA) and artificial neural networks–multilayer perceptron (ANN-MP), predictions were made about the concentrations of potentially toxic elements (PTEs) and their distribution in real space. In less than two decades (2007–2023) of fruitful collaboration, a large number of scientific works have been published: 188 scientific publications, 8 geochemical atlases and 23 chapters in monographs.
Ključne besede: chemical elements, distribution, pollution, soil, North Macedonia
Objavljeno: 25.03.2024; Ogledov: 103; Prenosov: 72
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9. Onkologija : učbenik za študente medicineDarja Arko, Primož Strojan, 2018 Opis: Ta knjiga je nastala v želji, da slovenskim študentom obeh medicinskih fakultet njihovi učitelji ponudijo celovit vpogled v področje onkologije od opredelitve obsega onkološke problematike in vzrokov za nastanek raka do zmožnosti moderne diagnostike in načel sodobnega zdravljenja posameznih vrst raka. Poglavja v učbeniku so zbrana v dveh sklopih: prvi - Splošna onkologija - ponuja vpogled v osnove onkologije in temeljne diagnostične in terapevtske načine; v drugem sklopu specialne onkologije so predstavljene posamezne vrste rakov z izjemo akutnih levkemij in kroničnih mieloproliferacijskih bolezni, ki so obravnavane v okviru drugih predmetov. Avtorji posameznih poglavij so bili izbrani glede na njihovo ekspertnost in poznavanje področja v želji ponuditi študentom čim bolj kakovostno učno gradivo.
Ključne besede: rak (medicina), kancerogeneza, imunologija, epidemiologija, presejanje, diagnostika, zdravljenje, paliativna oskrba, pozne posledice, urgentna stanja, otroci, dedni rak
Objavljeno: 18.04.2018; Ogledov: 5242; Prenosov: 1435
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10. Kamnolom apnenca v Podpeči pri Ljubljani in njegovi izdelkiBojan Djurić, Luka Gale, Rok Brajkovič, 2022 Opis: Kamnolom v naselju Podpeč pri Ljubljani velja za glavni kamnolom rimske kolonije Emone (Ljubljana). Obstoj antič-nega kamnoloma v Podpeči je bil do sedaj utemeljen le na podlagi makroskopske podobnosti med Členom litiotidnega apnenca, ki izdanja v Podpeči, in z njim povezanimi rimskimi spomeniki, odkritimi v Ljubljani. V okviru pričujočega dela smo skušali poiskati oprijemljive arheološke in geoarheološke dokaze za njegov obstoj. V skrajno severnem delu kamnoloma smo izvedli arheološko sondiranje, hkrati pa natančno določili sestavo apnenca na tem območju in v 288 izdelkih iz antične Emone. Sondiranje severno od modernega kamnoloma je odkrilo dobro ohranjene sledove rimsko-dobne kamnoseške dejavnosti. Hkrati je litološka analiza spomenikov iz Emone razkrila, da je kar 182 (ali 64 odstotkov) analiziranih spomenikov izdelanih iz apnenca, litološko identičnega različkom, ki izdanjajo v Podpeči. Ti različki se prostorsko grupirajo severno od modernega kamnoloma. Pri tem sicer ostaja odprto vprašanje pripadnosti nekaterih različkov apnenca v izdelkih, ki so brez diagnostičnih komponent in bi lahko pripadali tudi nekoliko starejšemu Členu krkinega apnenca. Rekonstrukcijo obsega starega kamnoloma omogoča primerjava faciesov izvornih litostratigrafskih enot in izdelkov, pa tudi historična analiza zgodnjih kartografskih in katastrskih dokumentov. Analiza najzgodnejših izdelkov je omogočila hipotezo o prihodu kamnosekov iz kamnoloma v Nabrežini.
Ključne besede: Slovenija, Podpeč, Emona, rimska doba, litiotidni apnenec, mikrofaciesna analiza, rimski in novoveški kamnolom, izdelki
Objavljeno: 21.07.2022; Ogledov: 662; Prenosov: 557
Celotno besedilo (28,23 MB)
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