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Title:Tekočinska biopsija pri raku
Authors:Dolinšek, Tanja (Author)
Grašič-Kuhar, Cvetka (Author)
Čemažar, Maja (Author)
Language:Slovenian
Tipology:1.04 - Professional Article
Organisation:LogoOI - Institute of Oncology
Abstract:V zadnjih letih smo v onkologiji priča hitremu napredku na področju biopsije telesnih tekočin oz. tekočinske biopsije. Tekočinska biopsija predstavlja analizo vzorca odvzete telesne tekočine (v onkologiji je to običajno kri), v katerem iščemo znake navzočnosti raka. V krvi lahko analiziramo cirkulirajočo prosto/cirkulirajočo tumorsko DNA (cf/ctDNA) iz tumorskih celic, eksosome, ki jih v kri sproščajo tumorske celice, in tudi cirkulirajoče tumorske celice (CTC). V pregledu predstavljamo najnovejša dognanja in raziskave na področju tekočinske biopsije pri raku in poleg uporabnosti izpostavljamo tudi njihove omejitve, ki jih bo treba natančno opredeliti, če bomo želeli to metodo uporabljati v vsakodnevni obravnavi bolnikov.
Keywords:tekočinska biopsija, onkologija, eksperimentalna onkologija
Year of publishing:2018
COBISS_ID:3032955 Link is opened in a new window
UDC:602
ISSN on article:1408-1741
OceCobissID:65324032 Link is opened in a new window
DOI:10.25670/oi2018-019on Link is opened in a new window
Views:497
Downloads:22
Files:.pdf Tekocinska_biopsija_pri_raku.pdf (136,00 KB)
 
Journal:Onkologija
Onkološki inštitut
 
Metadata:XML RDF-CHPDL DC-XML DC-RDF
Licenca:Priznanje avtorstva Novo okno
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Secondary language

Language:English
Title:Liquid biopsy in cancer
Abstract:Recently, new exciting developments in oncology have been made in the field of liquid biopsies. In liquid biopsy, samples of blood or other body fluids are analyzed for tumor-derived material. Tumor-derived material comprises cell-free circulating tumor DNA (cf/ctDNA), exosomes released by tumor cells, or circulating tumor cells themselves (CTC). In this review, we highlight the studies that summarize the state of the art in the field of liquid biopsy, and also represent the current challenges which should be addressed in the future to successfully implement liquid biopsy in a clinical setting.
Keywords:liquid biopsy, oncology, experimental oncology


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