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Title:Cirkulirajoče tumorske celice in njihov pomen pri raku dojke : pregled izsledkov dosedanjih raziskav
Authors:Marinko, Tanja (Author)
Lah Turnšek, Tamara (Author)
Serša, Gregor (Author)
Language:Slovenian
Tipology:1.04 - Professional Article
Organisation:Logo OI - Institute of Oncology
Keywords:tumor, onkologija, dojke, prognoza, zasevki
Year of publishing:2011
COBISS_ID:1194619 Link is opened in a new window
UDC:618.19-006.6
ISSN on article:1408-1741
OceCobissID:65324032 Link is opened in a new window
URN:URN:NBN:SI:doc-B98AV2ZQ
Views:2089
Downloads:506
Files:.pdf PDF - Presentation file, download (335,84 KB)
 
Journal:Onkologija
Onkološki inštitut
 
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License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.08.2018

Secondary language

Language:English
Title:Circlulation of tumor cells and their effect on breast cancer – reviewing the results of previous studies
Abstract:Circulating tumor cells (CTCs) are epithelial tumor cells detected in the peripheral blood of patients with solid malignant tumors. They originate from the primary tumor or metastatic sites. New techniques have been developed to isolate and characterise these cells, including the FDA-approved CellSearch, which are using mainly cytometric/antibody-based and molecular approaches. Recent advances in theories regarding metastasis support the role of early release of tumor cells in the neoplastic process. It has been found that phenotypic variation exists between the primary tumor and CTCs. Of particular interest is the difference found between primary tumor and CTC HER-2 status in both metastatic and early breast cancer. CTC enumeration has been incorporated into different fields of oncology as a prognostic marker, a tool to monitor therapy response, and a method to understand basic tumor characteristics. But currently, there is still no role for CTCs in clinical practice.

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