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Naslov:Clinical significance of histologic subtyping of malignant pleural mesothelioma
Avtorji:Brčić, Luka (Avtor)
Kern, Izidor (Avtor)
Jezik:Angleški jezik
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:LogoUKPBAG - Univerzitetna klinika za pljučne bolezni in alergijo Golnik
Povzetek: Malignant mesothelioma (MM) is uncommon, but very aggressive tumor arising from the mesothelial cells of pleura, pericardium, peritoneum, and tunica vaginalis. Despite multimodality treatments 5-year survival is only 5% after the diagnosis. Histology and TNM staging system are still the best prognostic factors. Furthermore, histologic subtype of MM determines the clinical management of the patients. According to the 2015 WHO classification, MM is divided into diffuse, localized and well differentiated papillary mesothelioma. Major histologic subtypes of diffuse MM, namely epithelioid, biphasic and sarcomatoid, have different prognosis. However, in the last decade it has become evident that more detailed subclassification and histologic/cytological characterization of MM have prognostic and perhaps predictive implications. In this review, major histologic subtypes and cytological features of MM are presented and their relation with prognosis and predictive biomarkers is discussed.
Ključne besede:malignant mesothelioma, epithelioid malignant mesothelioma, biphasic malignant mesothelioma, sarcomatoid malignant mesothelioma
Leto izida:2020
Založnik:AME Publishing Company
Izvor:Hong Kong
UDK:616-006
ISSN pri članku:2226-4477
OceCobissID:17120003 Povezava se odpre v novem oknu
COBISS_ID:17124867 Povezava se odpre v novem oknu
DOI:10.21037/tlcr.2020.03.38 Povezava se odpre v novem oknu
Opombe:Nasl. z nasl. zaslona; Opis vira z dne 27. 5. 2020;
Število ogledov:47
Število prenosov:30
Datoteke:URL URL - Predstavitvena datoteka, za dostop obiščite http://tlcr.amegroups.com/article/view/38662/pdf
 
Nadgradivo:Transl. lung cancer res.
Pioneer Bioscience
 
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
Avtorske pravice:Translational lung cancer research
Licenca:Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Novo okno
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