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2. Evolving strategies in the treatment of childhood rhabdomyosarcoma : Slovenian experienceŽiva Pohar-Marinšek, Jožica Anžič, Berta Jereb, 2001, izvirni znanstveni članek Povzetek: Background. Neoadjuvant chemotherapy (Cht) has changed the treatment of rhabdomyosarcoma (RMS) in children. The purpose of our study was to review thechildren treated for RMS between 1974 and 1996. Patients and methods. Fifty-one children, 1-15 years old, were included. Primary sites of tumour were: head and neck 15, orbit 6, genitourinary 12, extremity 9, torso 5 and paratesticular 4. Twelve patients were in stage 1, 10 in stage II, 26 in stage111 and 3 in stage IV. Of 43 histologically confirmed RMS 25 were embryonal, 13 alveolar, 1 botryoid, 1 spindle cell and 3 sarcoma NOS. In 8 patients, only fine needle aspiration biopsy (FNAB) was available. All patients had Cht, 29 neoadjuvant, 20 had surgery first, 40 had irradiation (RT), 2 stage IV patients had bone marrow transplant (ABMT). Multidrug Cht varied: VCR, AMD, and cyclophosphamide (VAC) were used in the 1970s, with Adriablastine (T2), methotrexat (MTX) and/or other drugs (T6, T11) in the 1980s; and in the 1990s, cyclophosphamide was replaced by ifosfamide (VAIA). The treatment was started with Cht in orbital and head and neck tumours and inthe majority of genitourinary tumours, but surgery was first in paratesticular and in the majority of extremity tumours. Results. The 3 patients with stage IV disease died. Of those with localised tumour, 34 (70%) were alive and well 5 years after treatment, 80% stage I, 75% stage II and 61%stage III. One patient died of heart failure, 3 of Cht toxicity and 1 of intereurrent disease. Conclusions. (Abstract truncated at 2000 characters) Objavljeno v DiRROS: 26.01.2024; Ogledov: 124; Prenosov: 28 Celotno besedilo (177,30 KB) |
3. Resections of pelvic bone and sacrum, Ljubljana experienceJanez Novak, Marjana Čuček-Pleničar, Darja Eržen, Franc Srakar, Mojca Senčar, Boštjan Baebler, Jožica Červek, Alenka Vodnik-Cerar, Matej Bračko, Živa Pohar-Marinšek, Jožica Anžič, 1997, izvirni znanstveni članek Objavljeno v DiRROS: 16.01.2024; Ogledov: 166; Prenosov: 40 Celotno besedilo (156,79 KB) |
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5. Pomen PIK3CA aktivirajočih mutacij za izid bolezni pri bolnicah z invazivnim lobularnim karcinomom dojke, zdravljenih z dopolnilno endokrino terapijoDomen Ribnikar, Valentina Jerič Horvat, Ivica Ratoša, Zachary Veitch, Biljana Grčar-Kuzmanov, Srdjan Novaković, Erik Langerholc, Maja Pohar Perme, Eitan Amir, Boštjan Šeruga, 2022, objavljeni povzetek strokovnega prispevka na konferenci Ključne besede: onkologija, rak dojke, kemoterapija Objavljeno v DiRROS: 27.01.2023; Ogledov: 370; Prenosov: 103 Celotno besedilo (46,13 KB) |
6. Prevalence of and factors associated with healthcare-associated infections in Slovenian acute care hospitals : results of the third national surveyIrena Klavs, Mojca Serdt, Aleš Korošec, Tatjana Lejko-Zupanc, Blaž Pečavar, 2019, izvirni znanstveni članek Povzetek: Introduction. In the third Slovenian national healthcare-associated infections (HAIs) prevalence survey, conducted within the European point prevalence survey of HAIs and antimicrobial use in acute care hospitals, we estimated the prevalence of all types of HAIs and identified factors associated with them. Methods. Patients were enrolled into a one-day cross-sectional study in November 2017. Descriptive analyses were performed to describe the characteristics of patients, their exposure to invasive procedures and the prevalence of different types of HAIs. Univariate and multivariate analyses of association of having at least one HAI with possible risk factors were performed to identify risk factors. Results. Among 5,743 patients, 4.4% had at least one HAI and an additional 2.2% were still treated for HAIs on the day of the survey, with a prevalence of HAIs of 6.6%. The prevalence of pneumoniae was the highest (1.8%), followed by surgical site infections (1.5%) and urinary tract infections (1.2%). Prevalence of blood stream infections was 0.3%. In intensive care units (ICUs), the prevalence of patients with at least one HAI was 30.6%. Factors associated with HAIs included central vascular catheter (adjusted odds ratio [aOR] 4.1; 95% confidence intervals [CI]: 3.1–5.4), peripheral vascular catheter (aOR 3.0; 95% CI: 2.3–3.9), urinary catheter (aOR 1.8; 95% CI: 1.4–2.3). Conclusions. The prevalence of HAIs in Slovenian acute care hospitals in 2017 was substantial, especially in ICUs. HAIs prevention and control is an important public health priority. National surveillance of HAIs in ICUs should be developed to support evidence-based prevention and control. Ključne besede: healthcare-associated infections, prevalence, survey, risk factors, Slovenia Objavljeno v DiRROS: 16.10.2020; Ogledov: 2275; Prenosov: 856 Celotno besedilo (255,15 KB) Gradivo ima več datotek! Več... |
7. A review of computational fluid dynamics (CFD) simulations of mixing in the pharmaceutical industrySimon Babnik, Vivian Erklavec Zajec, Blaž Oblak, Blaž Likozar, Andrej Pohar, 2020, kratki znanstveni prispevek Ključne besede: computational fluid dynamics (CFD), mixing vessel, batch reactor, phar-maceutical industry, bioreactors, crystallization, particulate flow, process optimization, active pharmaceutical ingredient (API) Objavljeno v DiRROS: 10.06.2020; Ogledov: 1833; Prenosov: 1192 Celotno besedilo (697,13 KB) Gradivo ima več datotek! Več... |
8. Navodila ginekologom za delo v programu ZORA : posodobitev 2011Maja Primic-Žakelj, Marjetka Uršič-Vrščaj, Ana Pogačnik, Urška Ivanuš, Andrej Možina, Živa Pohar-Marinšek, Mario Poljak, 2011, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Ključne besede: citodiagnostika, presejanje, papiloma virusi, kolposkopija, predrakave spremembe, diagnostika, zdravljenje, zborniki Objavljeno v DiRROS: 04.06.2020; Ogledov: 1692; Prenosov: 605 Celotno besedilo (4,75 MB) |
9. Navodila za poenotenje izvidov brisov materničnega vratuAna Pogačnik, Irena Srebotnik-Kirbiš, Alenka Repše-Fokter, Živa Pohar-Marinšek, Vivijana Snoj, Irena Kirar-Fazarinc, Maja Primic-Žakelj, 2005, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Ključne besede: bris, citopatologija Objavljeno v DiRROS: 04.06.2020; Ogledov: 1762; Prenosov: 516 Celotno besedilo (1,15 MB) |
10. Smernice diagnostike in zdravljenja diferenciranega raka ščitniceNikola Bešić, Andreja A. Schwarzbartl-Pevec, Andreja Klevišar Ivančič, Barbara Vidergar-Kralj, Barbara Gazić, Blaž Krhin, Branko Zakotnik, Cvetka Grašič-Kuhar, Damijan Bergant, Edvard Pirnat, Helena Gutnik, Ivana Žagar, Jerca Blazina, Katja Zaletel, Margareta Strojan Fležar, Marko Hočevar, Marta Dremelj, Nebojša Glumac, Olga Blatnik, Simona Gaberšček, Snežana Pavlović Djokić, Ulrika Klopčič, Veronika Kloboves-Prevodnik, Živa Pohar-Marinšek, 2017, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Ključne besede: rak ščitnice, diferencirani rak, zdravljenje, smernice Objavljeno v DiRROS: 27.05.2020; Ogledov: 1870; Prenosov: 610 Celotno besedilo (712,25 KB) |