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Query: "work type" (1) AND "fulltext" AND "organization" (Institute of Oncology) .

101 - 110 / 3800
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101.
Locally recurrent rectal cancer : treatment options
Vaneja Velenik, 2009, review article

Published in DiRROS: 08.03.2024; Views: 60; Downloads: 21
.pdf Full text (98,33 KB)

102.
103.
Acrospiroma of the left temporal region
Boris Jančar, 2009, other component parts

Published in DiRROS: 08.03.2024; Views: 54; Downloads: 20
.pdf Full text (433,26 KB)

104.
Irradiation of regionally advanced carcinoma of the penis
Borut Kragelj, 2009, original scientific article

Published in DiRROS: 08.03.2024; Views: 51; Downloads: 21
.pdf Full text (61,76 KB)

105.
Cisplatin-induced non-convulsive posterior reversible encephalopathy syndrome in a 41-year-old woman with metastatic malignant melanoma
Janja Ocvirk, Marko Boc, Martina Reberšek, Tanja Roš-Opaškar, 2009, original scientific article

Abstract: Background. Cisplatin, a widely used antineoplastic agent usually induces peripheral neuropathy, but can rarely also complicate with encephalopathy, with or without seizures. Case report. We report a case of a young patient with metastatic malignant melanoma with signs and symptoms of cisplatin-induced non-convulsive posterior reversible encephalopaty syndrome. Within the days shortly after the first cycle of cisplatin based chemotherapy the patient suffered from nausea, vomitus, headache, severe pain at the site of sub-cutaneous metastases and confusion. She later experienced somnolence, cortical blindness and aphasia, but without epileptic seizures. Conclusions. Cisplatin is an effective chemotherapeutic drug but also very toxic one and physicians using it must also be aware of possible encephalopathy.
Published in DiRROS: 08.03.2024; Views: 58; Downloads: 25
.pdf Full text (343,74 KB)

106.
Advances in the treatment of metastatic colorectal carcinoma
Janja Ocvirk, 2009, review article

Published in DiRROS: 08.03.2024; Views: 50; Downloads: 28
.pdf Full text (89,98 KB)

107.
Influence of magnesium sulphate infusion before total thyroidectomy on transient hypocalcemia - a randomised study
Nikola Bešić, Špela Žagar, Gašper Pilko, Barbara Perić, Marko Hočevar, 2008, original scientific article

Abstract: Background. Transient hypocalcemia is the most common complication after thyroidectomy. Normomagnesemia is needed for normal secretion of PTH and end-organ responsiveness. Our aim was to determine the influence of infusion of magnesium sulphate before thyroidectomy on the incidence of laboratory and clinical transient hypocalcemia. Methods. In our prospective study, 48 patients (5 men, 43 women; age 22-73 years, median 45 years), who underwent total or near-total thyroidectomy, were randomised preoperatively. Half of them received intravenously 4 ml of 1M magnesium sulphate at the beginning of the surgical procedure, the other half were the control group. Serum concentrations of calcium, ionised calcium, magnesium, phosphate, albumin and PTH were measured prior to surgery and on the first day after surgery. Results. Laboratory postoperative hypocalcemia was present in 27% of patients and 23% of patients had clinical signs and/or symptoms of postoperative hypocalcemia. The concentration of total calcium (p=0.024) and of albumin (p=0.01) was lower in the group that received magnesium sulphate. Conclusions.The patients who received infusion of magnesium sulphate before total thyroidectomy had lower concentration of total serum calcium and albuminin comparison to the control group. There was no statistical differencein the incidence of clinical transient hypocalcemia.
Published in DiRROS: 08.03.2024; Views: 55; Downloads: 20
.pdf Full text (72,12 KB)

108.
Extensive squamous cell carcinoma of the lower lid
Boris Jančar, 2008, professional article

Published in DiRROS: 08.03.2024; Views: 65; Downloads: 20
.pdf Full text (99,83 KB)

109.
In search of the shortest regimen: fractionation of a fully isoeffective combination of hyperfractionated and hypofractionated treatment
Andrej Strojnik, 2008, professional article

Abstract: Purpose. To analyze the possibility of reducing the number of fractions but maintaining the full biological effect of radiotherapy by varying the dose perfraction. Methods. An arbitrary treatment with a constant dose per fractionis substituted for a fully isoeffective combination of a hyperfractionated and hypofractionated treatment. The number of fractions of the combined treatment is derived. All calculations are based on the linear-quadratic model. Conclusions. Standard uniform fractionation requires the fewest fractions. Any variation in dose per fraction increases the number of fractions of a fully isoeffective treatment.
Published in DiRROS: 08.03.2024; Views: 60; Downloads: 15
.pdf Full text (66,71 KB)

110.
Optimization of electrode position and electric pulse amplitude in electrochemotherapy
Anže Županič, Selma Čorović, Damijan Miklavčič, 2008, original scientific article

Abstract: Background. In addition to the chemotherapeutic drug being present within the tumor during electric pulse delivery, successful electrochemotherapy requires the entire tumor volume to be subjected to a sufficiently high electric field,while the electric field in the surrounding healthy tissue is as low as possible to prevent damage. Both can be achieved with appropriate positioning of the electrodes and appropriate amplitude of electric pulses. Methods. We used 3D finite element numerical models and a genetic optimization algorithm to determine the optimum electrode configuration and optimum amplitude of electric pulses for treatment of three subcutaneous tumor models of different shapes and sizes and a realistic brain tumor model acquired from medical images. Results. In all four tumor cases, parallel needle electrode arrays were a better choice than hexagonal needle electrode arrays, since their utilization required less electric current and caused less healthy tissue damage. In addition, regardless of tumor geometry or needle electrode configuration, the optimum depth of electrode insertion was in all cases deeper than the deepest part of the tumor. Conclusions. Our optimization algorithm was able to determine the best electrode configuration in all four presented models and with further improvement it could be a useful tool in clinical electrochemotherapy treatment planning.
Published in DiRROS: 08.03.2024; Views: 68; Downloads: 22
.pdf Full text (248,14 KB)

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