141. Improving uncertainty of strain gauge bridge standardsMiha Hiti, 2018, objavljeni znanstveni prispevek na konferenci Povzetek: The article proposes a procedure for calibration of strain gauge bridge standards with improved relative calibration uncertainty. In contrast to a typical calibration with voltage ratio standards or comparison calibration with other bridge standards, the proposed procedure uses a calibrated reference bridge amplifier, additionally evaluated using combinatorial calibration technique to improve its calibration uncertainty. The resulting uncertainty of ratio steps referenced to zero ratio step is lower than the traditional uncertainty achieved through direct independent traceability to mVV−1 ratio values. The proposed procedure enables direct application of the calibrated bridge standard values with low relative uncertainty for calibration of bridge amplifiers, without the need for additional combinatorial evaluation of each individual bridge amplifier. Ključne besede: voltage ratio, linearity check, bridge standard, calibration Objavljeno v DiRROS: 05.04.2024; Ogledov: 50; Prenosov: 38 Celotno besedilo (775,45 KB) Gradivo ima več datotek! Več... |
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148. Consequence of the introduction of routine FCH PET/CT imaging for patients with prostate cancer : a dual centre surveyMarina Hodolič, Laure Michaud, V. Huchet, S. Balogova, V. Nataf, K. Kerrou, M. Vereb, Jurij Fettich, Jean-Noël Talbot, 2014, izvirni znanstveni članek Povzetek: Background. Fluorocholine(18F) (FCH) was introduced at the beginning of April 2010 in France, Slovenia and three other EU member states for the localisation of bone metastases of prostate cancer with PET. The aim of the study was to compare the evolution of diagnostic imaging in patients with prostate cancer using a new radiopharmaceutical FCH, observed in France and in Slovenia, and to quantify the consequence of the results of new imaging modality on the detection rate of abnormal metastases and recurrences of prostate cancer.Patients and methods. In two centres (France/Slovenia), a survey of the number of nuclear medicine examinations in patients with prostate cancer was performed, covering 5 quarters of the year since the introduction of FCH. For each examination, the clinical and biological circumstances were recorded, as well as the detection of bone or soft tissue foci.Results. Six hundred and eighty-eight nuclear medicine examinations were performed impatients with prostate cancer. Nuclear medicine examinations were performed for therapy monitoring and follow-up in 23% of cases. The number of FCH PET/CT grew rapidly between the 1st and 5th period of the observation (+220%), while the number of bone scintigraphies (BS) and fluoride(18F) PET/CTs decreased (-42% and -23% respectively). Fluorodeoxyglucose(18F) (FDG) PET/CT remained limited to few cases of castrate-resistant or metastatic prostate cancer in Paris. The proportion of negative results was significantly lower with FCH PET/CT (14%) than with BS (49%) or fluoride(18F) PET/CT (54%). For bone metastases, the detection rate was similar, but FCH PET/CT was performed on average at lower prostate-specific antigen (PSA) levels and was less frequently doubtful (4% vs. 28% for BS). FCH PET/CT also showed foci in prostatic bed (53% of cases) or in soft tissue (35% of cases).Conclusions. A rapid development of FCH PET/CT was observed in both centres and led to a higher detection rate of prostate cancer lesions. Ključne besede: prostate cancer, PET/CT, fluorocholine (FCH), fluoride(18F), bone scintigraphy, indication of imaging, prostata, rak (medicina), slikovna diagnostika Objavljeno v DiRROS: 04.04.2024; Ogledov: 71; Prenosov: 38 Celotno besedilo (595,04 KB) Gradivo ima več datotek! Več... |
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