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MRI evaluation of tibial tunnel wall cortical bone formation after platelet-rich plasma applied during anterior cruciate ligament reconstruction
Mitja Rupreht, Matjaž Vogrin, Mohsen Hussein, 2013, izvirni znanstveni članek

Povzetek: Background. After anterior cruciate ligament (ACL) reconstruction, formation of cortical sclerotic bone encircling the femoral and tibial tunnel is a part of intratunnel graft healing. During the physiological cascades of soft tissue healing and bone growth, cellular and hormonal factors play an important role. The purpose of this study was to noninvasively but quantitatively assess the effect of intraoperatively applied platelet-rich plasma (PRP) on the formation of cortical bone encircling the tibial tunnel. Patients and methods. In fifty patients, standard arthroscopic ACL reconstructions were performed. The PRP group (n = 25) received a local application of PRP while the control group (n = 25) did not receive PRP. The proximal tibial tunnel was examined by MRI in the paraxial plane where the portion of the tibial tunnel wall circumference consisting of sclerotic cortical bone was assessed with testing occurring at one, two and a half and six months after surgery. Results. At one month after surgery, differences between the groups in the amount of cortical sclerotic bone encircling the tunnel were not significant (p = 0.928). At two and a half months, the sclerotic portion of the tunnel wall in the PRP group (36.2%) was significantly larger than in the control (22.5%) group (p = 0.004). At six months, the portion of sclerotic bone in the PRP group (67.1%) was also significantly larger than in the control (53.5%) group (p = 0.003). Conclusions. Enhanced cortical bone formation encircling the tibial tunnel at 2.5 and 6 months after ACL graft reconstruction results from locally applied platelet-rich plasma.
Objavljeno v DiRROS: 22.03.2024; Ogledov: 47; Prenosov: 24
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Insight into tetramolecular DNA G-quadruplexes associated with ALS and FTLD : cation interactions and formation of higher-ordered structure
Matja Zalar, Baifan Wang, Janez Plavec, Primož Šket, 2023, izvirni znanstveni članek

Ključne besede: ALS, FTLD, DNA, c9orf7, NMR, quadruplex, cations
Objavljeno v DiRROS: 06.09.2023; Ogledov: 258; Prenosov: 152
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4.
Lower-limb muscle contractile properties, explosive power and the subjective response of elite soccer players to the Covid-19 lockdown
Armin Paravlić, Boštjan Šimunič, Saša Pišot, Matej Kleva, Kaja Teraž, Matjaž Vogrin, Uroš Marušič, Rado Pišot, 2022, izvirni znanstveni članek

Povzetek: The present study examined the effects of the lockdown period on basic anthropometric measures, countermovement jumping performance, skeletal muscle contractile properties derived from tensiomyography (TMG), injury incidence, and self-assessed general well-being in elite soccer players. A total of 266 players were assessed before (PRE) and 32 players were reassessed 11 days after (POST) the COVID-19 period. Significant changes in the TMG parameters were observed POST compared to PRE: contraction time (Tc) increased from 6% to 50% in vastus lateralis [VL] (p = 0.009) and biceps femoris [BF] (p < 0.001), respectively; whereas radial displacement (Dm) increased for 19% in BF (p = 0.036) and 17% in VL (p < 0.001), respectively. Jumping performance remained unchanged from PRE to POST In addition, athletes rated the lockdown period as a positive event and felt psychologically better during the lockdown, primarily because they spent more time with family members and friends. Although there were no differences in any of the variables describing lower limb muscle power following the two-month lockdown, the altered contractile properties of the assessed muscles suggest suboptimal conditioning of the football players.
Ključne besede: football, male football, power, explosive power, tensiomyography, coronavirus, covid-19, pandemics, lockdown
Objavljeno v DiRROS: 06.01.2022; Ogledov: 745; Prenosov: 471
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