The clinical relevance of oliguria in the critically ill patient : analysis of a large observational database
16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient-oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged-oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent-oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19%1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97%1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.]]>
© The Author(s). 2020
2020
2020-11-18 13:34:52
1033
critical care, critical illness, urine, oliguria, kidney, renal insufficiency, kidney diseases, acute kidney failure, mortality, urine output, renal replacement therapy
oskrba kritično bolnih, kritično stanje, urin, oligurija, ledvica, renalna insuficienca, bolezni ledvic, akutna ledvična odpoved, umrljivost, izločanje urina, nadomestno zdravljenje ledvične odpovedi
Springer Nature
Jean Louis
Vincent
70
Andrew
Ferguson
70
Peter
Pickkers
70
Stephan M.
Jakob
70
Ulrich
Jaschinski
70
Ghaleb A.
Almekhlafi
70
Marc
Leone
70
Majid
Mokhtari
70
Luis E.
Fontes
70
Philippe R.
Bauer
70
Yasser
Sakr
70
Viktorija
Tomič
60
Gorazd
Voga
927
Erik
Rupnik
927
Lučka
Kosec
927
Milena
Kerin-Povšič
927
Irena
Osojnik
927
Viktorija
Tomič
927
Andreja
Sinkovič
927
UDK
4
616.1/.4
ISSN pri članku
9
1466-609X
DOI
15
10.1186/s13054-020-02858-x
COBISS_ID
3
37575171
OceCobissID
13
1137983
RAZ_Vincent_Jean_Louis_i2020.pdf
745203
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2020-11-18 13:34:55